The interim Independent Science and Partnership Council presents a work plan and budget for 2010 and seeks Fund Council endorsement for the outline plan and proposed budget of USD 3.572 million. The document presents the transition from the Science Council (with a report on the completion of SC activities in the last biennium) and the interpretation of the new mandate of the ISPC. These represent a mixture, in the transitional year of 2010, of continuing and new functions. However the Work plan is developed in the context of the 2010/2011 biennium and places emphasis on iISPC activities with an anticipated enlargement of impact assessment activities, science foresight and the mobilization of science. This report was discussed at the first Fund Council meeting in February 2010.